Given a group $G$ and a partial factor set $\sigma $ of $G,$ we introduce the twisted partial group algebra $\kappa_{par}^{\sigma}G,$ which governs the partial projective $\sigma $-representations of $G$ into algebras over a field $\kappa .$ Using the relation between partial projective representations and twisted partial actions we endow $\kappa_{par}^{\sigma}G$   with the structure of a crossed product by a twisted partial action of $G$ on a commutative subalgebra of $\kappa_{par}^{\sigma}G.$   Then, we use twisted partial group algebras to obtain a first quadrant Grothendieck spectral sequence converging to the Hochschild homology of the crossed product $A\ast_{\Theta} G,$ involving the Hochschild homology of $A$ and the partial homology of $G,$ where ${\Theta}$ is a unital twisted partial action of $G$ on a $\kappa$-algebra $A$ with a $\kappa $-based twist. An analogous third quadrant cohomological spectral sequence is also obtained. This is a joint work with Emmanuel Jerez.